Abstract

Abstract

Pulmonary Langerhans cell histiocytosis is an uncommon interstitial lung disease that results from the accumulation of cells known as Langerhans cells in the lung. It primarily affects young smokers. High resolution chest computed tomography findings are typical for the disease. Open lung biopsy is an effective method in the diagnosis of the disease. In the present report we describe two patients with pulmonary Langerhans cell histiocytosis diagnosed by open lung biopsy.